Based on FDA's careful review of the scientific literature on the health risks associated with cigarette smoking, evaluation of the public's general awareness and knowledge of those health risks, and assessment of the Agency's own consumer research on potential revised warning statements, FDA determined there is sufficient support to propose adjusting some of the text of the TCA statements, as authorized by section 4(d) of the FCLAA (as amended by section 202(b) of the Tobacco Control Act)
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Clinical trials analysing a class of cancer medication called small-molecule tyrosine kinase inhibitors, which targets a family of proteins that are mutated in many types of cancer, showed that never-smokers, individuals with adenocarcinoma, women and people with east Asian ancestry were more likely to respond well to the drugs than people with a history of smoking 2
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